5,6-diiodo-1H-benzotriazole: new TBBt analogue that minutely affects mitochondrial activity

4,5,6,7-Tetrabromo-1H-benzotriazole is widely used as the reference ATP-competitive inhibitor of protein kinase CK2. Herein, we study its new analogs: 5,6-diiodo- and 5,6-diiodo-4,7-dibromo-1H-benzotriazole. We used biophysical (MST, ITC) and biochemical (enzymatic assay) methods to describe the int...

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Detalles Bibliográficos
Autores principales: Paprocki, Daniel, Winiewska-Szajewska, Maria, Speina, Elżbieta, Kucharczyk, Róża, Poznański, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654832/
https://www.ncbi.nlm.nih.gov/pubmed/34880390
http://dx.doi.org/10.1038/s41598-021-03136-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654832/
https://www.ncbi.nlm.nih.gov/pubmed/34880390
http://dx.doi.org/10.1038/s41598-021-03136-8

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