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5,6-diiodo-1H-benzotriazole: new TBBt analogue that minutely affects mitochondrial activity
4,5,6,7-Tetrabromo-1H-benzotriazole is widely used as the reference ATP-competitive inhibitor of protein kinase CK2. Herein, we study its new analogs: 5,6-diiodo- and 5,6-diiodo-4,7-dibromo-1H-benzotriazole. We used biophysical (MST, ITC) and biochemical (enzymatic assay) methods to describe the int...
Autores principales: | Paprocki, Daniel, Winiewska-Szajewska, Maria, Speina, Elżbieta, Kucharczyk, Róża, Poznański, Jarosław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654832/ https://www.ncbi.nlm.nih.gov/pubmed/34880390 http://dx.doi.org/10.1038/s41598-021-03136-8 |
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