Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

To elucidate the mechanisms underlying the reduced incidence of brain tumors in children with Neurofibromatosis type 1 (NF1) and asthma, we leverage Nf1 optic pathway glioma (Nf1(OPG)) mice, human and mouse RNAseq data, and two different experimental asthma models. Following ovalbumin or house dust...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Jit, Sanapala, Shilpa, Cobb, Olivia, Bewley, Alice, Goldstein, Andrea K., Cordell, Elizabeth, Ge, Xia, Garbow, Joel R., Holtzman, Michael J., Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654836/
https://www.ncbi.nlm.nih.gov/pubmed/34880260
http://dx.doi.org/10.1038/s41467-021-27455-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654836/
https://www.ncbi.nlm.nih.gov/pubmed/34880260
http://dx.doi.org/10.1038/s41467-021-27455-6

Ejemplares similares