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Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia

To elucidate the mechanisms underlying the reduced incidence of brain tumors in children with Neurofibromatosis type 1 (NF1) and asthma, we leverage Nf1 optic pathway glioma (Nf1(OPG)) mice, human and mouse RNAseq data, and two different experimental asthma models. Following ovalbumin or house dust...

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Detalles Bibliográficos
Autores principales:	Chatterjee, Jit, Sanapala, Shilpa, Cobb, Olivia, Bewley, Alice, Goldstein, Andrea K., Cordell, Elizabeth, Ge, Xia, Garbow, Joel R., Holtzman, Michael J., Gutmann, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654836/ https://www.ncbi.nlm.nih.gov/pubmed/34880260 http://dx.doi.org/10.1038/s41467-021-27455-6

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