Cargando…
Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents
Transketolase (TK) has been previously engineered, using semi-rational directed evolution and substrate walking, to accept increasingly aliphatic, cyclic, and then aromatic substrates. This has ultimately led to the poor water solubility of new substrates, as a potential bottleneck to further exploi...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654844/ https://www.ncbi.nlm.nih.gov/pubmed/34880340 http://dx.doi.org/10.1038/s41598-021-03001-8 |