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Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway

Lung adenocarcinoma (LUAD) belongs to a subgroup of non-small cell lung cancer (NSCLC) with an increasing incidence all over the world. Tanshinone IIA (TSA), an active compound of Salvia miltiorrhiza Bunge., has been found to have anti-tumor effects on many tumors, but its anti-LUAD effect and its m...

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Detalles Bibliográficos
Autores principales: Li, Ziheng, Zhang, Ying, Zhou, Yuan, Wang, Fuqian, Yin, Chao, Ding, Li, Zhang, Shunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654884/
https://www.ncbi.nlm.nih.gov/pubmed/34880385
http://dx.doi.org/10.1038/s41598-021-03166-2