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PET imaging of brain aromatase in humans and rhesus monkeys by (11)C-labeled cetrozole analogs

Aromatase is an estrogen synthetic enzyme that plays important roles in brain functions. To quantify aromatase expression in the brain by positron emission tomography (PET), we had previously developed [(11)C]cetrozole, which showed high specificity and affinity. To develop more efficient PET tracer...

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Detalles Bibliográficos
Autores principales: Takahashi, Kayo, Hosoya, Takamitsu, Onoe, Kayo, Mori, Tomoko, Tazawa, Shusaku, Mawatari, Aya, Wada, Yasuhiro, Watanabe, Yumiko, Doi, Hisashi, Watanabe, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654920/
https://www.ncbi.nlm.nih.gov/pubmed/34880350
http://dx.doi.org/10.1038/s41598-021-03063-8