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Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

The complement system has long been recognized as a potential druggable target for a variety of inflammatory conditions. Very few complement inhibitors have been approved for clinical use, but a great number are in clinical development, nearly all of which systemically inhibit complement. There are...

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Detalles Bibliográficos
Autores principales: Zheng, Chaowen, Ricci, Jerec, Zhang, Qinqin, Alawieh, Ali, Yang, Xiaofeng, Nadig, Satish, He, Songqing, Engel, Pablo, Jin, Junfei, Atkinson, Carl, Tomlinson, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654931/
https://www.ncbi.nlm.nih.gov/pubmed/34899752
http://dx.doi.org/10.3389/fimmu.2021.785229