Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications

DNA double-strand breaks are a major threat to cellular survival and genetic integrity. In addition to high fidelity repair, three intrinsically mutagenic DNA break repair routes have been described, i.e. single-strand annealing (SSA), polymerase theta-mediated end-joining (TMEJ) and residual ill-de...

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Detalles Bibliográficos
Autores principales: Kamp, J. A., Lemmens, B. B. L. G., Romeijn, R. J., Changoer, S. C., van Schendel, R., Tijsterman, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654963/
https://www.ncbi.nlm.nih.gov/pubmed/34880204
http://dx.doi.org/10.1038/s41467-021-27408-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654963/
https://www.ncbi.nlm.nih.gov/pubmed/34880204
http://dx.doi.org/10.1038/s41467-021-27408-z

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