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Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma

Tumour lineage plasticity is an emerging hallmark of aggressive tumours. Tumour cells usually hijack developmental signalling pathways to gain cellular plasticity and evade therapeutic targeting. In the present study, the secreted protein growth and differentiation factor 1 (GDF1) is found to be clo...

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Detalles Bibliográficos
Autores principales: Cheng, Wei, Li, Hao-Long, Xi, Shao-Yan, Zhang, Xiao-Feng, Zhu, Yun, Le Xing, Mo, Yan-Xuan, Li, Mei-Mei, Kong, Fan-En, Zhu, Wen-Jie, Chen, Xiao-Gang, Cui, Hui-Qing, Cao, Zhi-Ming, Gong, Yuan-Feng, Tang, Yun-Qiang, Zhang, Yan, Guan, Xin-Yuan, Ma, Ning-Fang, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654996/
https://www.ncbi.nlm.nih.gov/pubmed/34880251
http://dx.doi.org/10.1038/s41467-021-27525-9