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Plasticity within the barrel domain of BamA mediates a hybrid-barrel mechanism by BAM

In Gram-negative bacteria, the biogenesis of β-barrel outer membrane proteins is mediated by the β-barrel assembly machinery (BAM). The mechanism employed by BAM is complex and so far- incompletely understood. Here, we report the structures of BAM in nanodiscs, prepared using polar lipids and native...

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Detalles Bibliográficos
Autores principales: Wu, Runrun, Bakelar, Jeremy W., Lundquist, Karl, Zhang, Zijian, Kuo, Katie M., Ryoo, David, Pang, Yui Tik, Sun, Chen, White, Tommi, Klose, Thomas, Jiang, Wen, Gumbart, James C., Noinaj, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655018/
https://www.ncbi.nlm.nih.gov/pubmed/34880256
http://dx.doi.org/10.1038/s41467-021-27449-4