Osteosarcoma cell proliferation suppression via SHP-2-mediated inactivation of the JAK/STAT3 pathway by tubocapsenolide A

INTRODUCTION: Previously, we have reported a withanolide-type steroid, named tubocapsenolide A (TA), which shows potent anti-proliferative activity in several cancer cell lines. However, its inhibitory effect on the Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway...

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Detalles Bibliográficos
Autores principales: Zhu, Dongrong, Chen, Chen, Liu, Xiaoqin, Wang, Sibei, Zhu, Jiangmin, Zhang, Hao, Kong, Lingyi, Luo, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655134/
https://www.ncbi.nlm.nih.gov/pubmed/35024182
http://dx.doi.org/10.1016/j.jare.2021.06.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655134/
https://www.ncbi.nlm.nih.gov/pubmed/35024182
http://dx.doi.org/10.1016/j.jare.2021.06.004

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