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Osteosarcoma cell proliferation suppression via SHP-2-mediated inactivation of the JAK/STAT3 pathway by tubocapsenolide A

INTRODUCTION: Previously, we have reported a withanolide-type steroid, named tubocapsenolide A (TA), which shows potent anti-proliferative activity in several cancer cell lines. However, its inhibitory effect on the Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway...

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Detalles Bibliográficos
Autores principales:	Zhu, Dongrong, Chen, Chen, Liu, Xiaoqin, Wang, Sibei, Zhu, Jiangmin, Zhang, Hao, Kong, Lingyi, Luo, Jianguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655134/ https://www.ncbi.nlm.nih.gov/pubmed/35024182 http://dx.doi.org/10.1016/j.jare.2021.06.004

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