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Progranulin as a Potential Therapeutic Target in Immune-Mediated Diseases

Progranulin (PGRN), a secretory glycoprotein consisting of 593 amino acid residues, is a key actor and regulator of multiple system functions such as innate immune response and inflammation, as well as tissue regeneration. Recently, there is emerging evidence that PGRN is protective in the developme...

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Detalles Bibliográficos
Autores principales: Lan, Yue-Jiao, Sam, Napoleon Bellua, Cheng, Ming-Han, Pan, Hai-Feng, Gao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655512/
https://www.ncbi.nlm.nih.gov/pubmed/34898994
http://dx.doi.org/10.2147/JIR.S339254