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Progranulin as a Potential Therapeutic Target in Immune-Mediated Diseases
Progranulin (PGRN), a secretory glycoprotein consisting of 593 amino acid residues, is a key actor and regulator of multiple system functions such as innate immune response and inflammation, as well as tissue regeneration. Recently, there is emerging evidence that PGRN is protective in the developme...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655512/ https://www.ncbi.nlm.nih.gov/pubmed/34898994 http://dx.doi.org/10.2147/JIR.S339254 |