Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched

Reproducibility of expression patterns in iPSC-derived cells from different labs is an important first step in ensuring replication of biochemical or functional assays that are performed in different labs. Here we show that reproducible gene expression patterns from iPSCs and iPSC-derived neurons ma...

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Detalles Bibliográficos
Autores principales: Reed, Xylena, Cobb, Melanie M., Skinbinski, Gaia, Roosen, Dorien, Kaganovich, Alice, Ding, Jinhui, Finkbeiner, Steve, Cookson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655646/
https://www.ncbi.nlm.nih.gov/pubmed/34626895
http://dx.doi.org/10.1016/j.scr.2021.102558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655646/
https://www.ncbi.nlm.nih.gov/pubmed/34626895
http://dx.doi.org/10.1016/j.scr.2021.102558

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