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Poly(acrylamide-co-N,N′-methylenebisacrylamide) Monoliths for High-Peak-Capacity Hydrophilic-Interaction Chromatography–High-Resolution Mass Spectrometry of Intact Proteins at Low Trifluoroacetic Acid Content

[Image: see text] In this study, we optimized a polymerization mixture to synthesize poly(acrylamide-co-N,N′-methylenebisacrylamide) monolithic stationary phases for hydrophilic-interaction chromatography (HILIC) of intact proteins. Thermal polymerization was performed, and the effects of varying th...

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Detalles Bibliográficos
Autores principales: Passamonti, Marta, de Roos, Chiem, Schoenmakers, Peter J., Gargano, Andrea F.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655738/
https://www.ncbi.nlm.nih.gov/pubmed/34807576
http://dx.doi.org/10.1021/acs.analchem.1c03473