Inhalation exposure to 2-ethyl-1-hexanol causes hepatomegaly and transient lipid accumulation without induction of peroxisome proliferator-activated receptor alpha in mice

2-Ethyl-1-hexanol (2EH) is a volatile organic compound known to cause sick building syndrome. However, 2EH-induced hepatotoxicity has been mainly evaluated in experiments orally administering 2EH as a metabolite of di(2-ethylhexyl) phthalate. To evaluate the hepatotoxicity risk of 2EH as an indoor a...

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Detalles Bibliográficos
Autores principales: WAKAYAMA, Takanari, ITO, Yuki, MIYAKE, Mio, NOMASA, Karin, SAKAI, Kiyoshi, OYA, Naoko, SATO, Hirotaka, OHNO, Hiroyuki, KAMIJIMA, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Occupational Safety and Health, Japan 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655744/
https://www.ncbi.nlm.nih.gov/pubmed/34588381
http://dx.doi.org/10.2486/indhealth.2020-0252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655744/
https://www.ncbi.nlm.nih.gov/pubmed/34588381
http://dx.doi.org/10.2486/indhealth.2020-0252

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