2-Amino-4,5-dihydrothiophene-3-carbonitriles: A New Synthesis, Quantum Chemical Studies, and Mannich-Type Reactions Leading to New Hexahydrothieno[2,3-d]pyrimidines

[Image: see text] trans-2-Amino-4-aryl-5-benzoyl-4,5-dihydrothiophene-3-carbonitriles were prepared either by the reaction of 3-aryl-2-cyanothioacrylamides with α-thiocyanatoacetophenone or by the Michael-type addition of cyanothioacetamide to α-bromochalcones followed by intramolecular cyclization....

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Detalles Bibliográficos
Autores principales: Dotsenko, Victor V., Bespalov, Alexander V., Vashurin, Arthur S., Aksenov, Nicolai A., Aksenova, Inna V., Chigorina, Elena A., Krivokolysko, Sergey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655800/
https://www.ncbi.nlm.nih.gov/pubmed/34901606
http://dx.doi.org/10.1021/acsomega.1c04141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655800/
https://www.ncbi.nlm.nih.gov/pubmed/34901606
http://dx.doi.org/10.1021/acsomega.1c04141

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