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α4/α9 Integrins Coordinate Epithelial Cell Migration Through Local Suppression of MAP Kinase Signaling Pathways

Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury. Integrin receptors indirectly link the ECM to the cell cytoskeleton through large protein complexes called focal adhesions (FA). FA also function a...

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Detalles Bibliográficos
Autores principales: Hight-Warburton, Willow, Felix, Robert, Burton, Andrew, Maple, Hannah, Chegkazi, Magda S., Steiner, Roberto A., McGrath, John A., Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655878/
https://www.ncbi.nlm.nih.gov/pubmed/34900996
http://dx.doi.org/10.3389/fcell.2021.750771