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Chemoselective Attachment of the Water-Soluble Dark Quencher Hydrodabcyl to Amino Groups in Peptides and Preservation of Its Spectroscopic Properties over a Wide pH Range

[Image: see text] The water-soluble quencher hydrodabcyl can be activated as an N-succinimidyl ester that is readily accessible from crude hydrodabcyl and storable for a long time. With primary and secondary amines, it reacts swiftly and chemoselectively, even in the presence of other competing nucl...

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Detalles Bibliográficos
Autores principales: Kempf, Oxana, Ullmann, G. Matthias, Schobert, Rainer, Kempf, Karl, Bombarda, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8655893/
https://www.ncbi.nlm.nih.gov/pubmed/34901640
http://dx.doi.org/10.1021/acsomega.1c04891