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Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes
BACKGROUND: Transdifferentiation describes transformation in vivo of specialized cells from one lineage into another. While there is extensive literature on forced induction of lineage reprogramming in vitro, endogenous mechanisms that govern transdifferentiation remain largely unknown. The observat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656028/ https://www.ncbi.nlm.nih.gov/pubmed/34886891 http://dx.doi.org/10.1186/s13059-021-02555-0 |