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Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes

BACKGROUND: Transdifferentiation describes transformation in vivo of specialized cells from one lineage into another. While there is extensive literature on forced induction of lineage reprogramming in vitro, endogenous mechanisms that govern transdifferentiation remain largely unknown. The observat...

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Detalles Bibliográficos
Autores principales:	Rezaei-Lotfi, Saba, Vujovic, Filip, Simonian, Mary, Hunter, Neil, Farahani, Ramin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656028/ https://www.ncbi.nlm.nih.gov/pubmed/34886891 http://dx.doi.org/10.1186/s13059-021-02555-0

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