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Increased Leishmania infantum resistance to miltefosine and amphotericin B after treatment of a dog with miltefosine and allopurinol

BACKGROUND: Leishmania infantum is the most important etiological agent of visceral leishmaniasis in the Americas and Mediterranean region, and the dog is the main host. Miltefosine was authorized to treat canine leishmaniasis (CanL) in Brazil in 2017, but there is a persistent fear of the emergence...

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Detalles Bibliográficos
Autores principales: Gonçalves, Gustavo, Campos, Monique Paiva, Gonçalves, Alessandra Silva, Medeiros, Lia Carolina Soares, Figueiredo, Fabiano Borges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656069/
https://www.ncbi.nlm.nih.gov/pubmed/34886876
http://dx.doi.org/10.1186/s13071-021-05100-x