Total synthesis of remdesivir()

Remdesivir, the first drug approved by the FDA to treat COVID-19, is in high demand for patients infected with the SARS-CoV-2 virus. Herein, we report a facile approach minimizing the protecting group manipulations to afford remdesivir in good overall yield.

Detalles Bibliográficos
Autores principales: Kumar Palli, Kishore, Ghosh, Palash, Krishna Avula, Shiva, Sridhara Shanmukha Rao, B., Patil, Amol D., Ghosh, Subhash, Sudhakar, Gangarajula, Raji Reddy, Chada, Mainkar, Prathama S., Chandrasekhar, Srivari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656175/
https://www.ncbi.nlm.nih.gov/pubmed/34908617
http://dx.doi.org/10.1016/j.tetlet.2021.153590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656175/
https://www.ncbi.nlm.nih.gov/pubmed/34908617
http://dx.doi.org/10.1016/j.tetlet.2021.153590

Ejemplares similares