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Prime Editing for Inherited Retinal Diseases

Inherited retinal diseases (IRDs) are chronic, hereditary disorders that lead to progressive degeneration of the retina. Disease etiology originates from a genetic mutation—inherited or de novo—with a majority of IRDs resulting from point mutations. Given the plethora of IRDs, to date, mutations tha...

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Detalles Bibliográficos
Autores principales: da Costa, Bruna Lopes, Levi, Sarah R., Eulau, Eric, Tsai, Yi-Ting, Quinn, Peter M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656220/
https://www.ncbi.nlm.nih.gov/pubmed/34901928
http://dx.doi.org/10.3389/fgeed.2021.775330