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Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern

The effect of emerging SARS-CoV-2 variants on vaccine efficacy is of critical importance. In this study, the potential impact of mutations that facilitate escape from the cytotoxic cellular immune response in these new virus variants for the 551 most abundant HLA class I alleles was analyzed. Comput...

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Detalles Bibliográficos
Autores principales: Martín-Galiano, Antonio J., Díez-Fuertes, Francisco, McConnell, Michael J., López, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656262/
https://www.ncbi.nlm.nih.gov/pubmed/34899692
http://dx.doi.org/10.3389/fimmu.2021.732693