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Inhibition of PI3Kδ Differentially Regulates Poly I:C– and Human Metapneumovirus–Induced PD–L1 and PD–L2 Expression in Human Bronchial Epithelial Cells

Bronchial epithelial cells are front sentinels eliciting innate and adaptive immunity to respiratory viral pathogens. Recognition of viral double-stranded RNA induces antiviral interferon (IFN) responses in bronchial epithelial cells. Co-inhibitory molecules programmed cell death 1 ligand 1 (PD-L1)...

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Detalles Bibliográficos
Autores principales: Ogawa, Tomohiro, Kan-o, Keiko, Shiota, Ayaka, Fujita, Akitaka, Ishii, Yumiko, Fukuyama, Satoru, Matsumoto, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656419/
https://www.ncbi.nlm.nih.gov/pubmed/34899719
http://dx.doi.org/10.3389/fimmu.2021.767666