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Inhibition of PI3Kδ Differentially Regulates Poly I:C– and Human Metapneumovirus–Induced PD–L1 and PD–L2 Expression in Human Bronchial Epithelial Cells
Bronchial epithelial cells are front sentinels eliciting innate and adaptive immunity to respiratory viral pathogens. Recognition of viral double-stranded RNA induces antiviral interferon (IFN) responses in bronchial epithelial cells. Co-inhibitory molecules programmed cell death 1 ligand 1 (PD-L1)...
Autores principales: | Ogawa, Tomohiro, Kan-o, Keiko, Shiota, Ayaka, Fujita, Akitaka, Ishii, Yumiko, Fukuyama, Satoru, Matsumoto, Koichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656419/ https://www.ncbi.nlm.nih.gov/pubmed/34899719 http://dx.doi.org/10.3389/fimmu.2021.767666 |
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