Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition

SIMPLE SUMMARY: Pancreatic cancer remains an incurable cancer with a gloomy prognosis and a median survival of months since the time of diagnosis. Disappointingly, no significant improvement in clinical outcomes has been achieved for the last fifty years. Cancer stem cells (CSCs) are suggested to be...

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Detalles Bibliográficos
Autores principales: Gajate, Consuelo, Gayet, Odile, Fraunhoffer, Nicolas A., Iovanna, Juan, Dusetti, Nelson, Mollinedo, Faustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656492/
https://www.ncbi.nlm.nih.gov/pubmed/34885233
http://dx.doi.org/10.3390/cancers13236124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656492/
https://www.ncbi.nlm.nih.gov/pubmed/34885233
http://dx.doi.org/10.3390/cancers13236124

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