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NDRG2 Expression in Breast Cancer Cells Downregulates PD-L1 Expression and Restores T Cell Proliferation in Tumor-Coculture

SIMPLE SUMMARY: N-myc downstream-regulated gene 2 (NDRG2) is a candidate tumor suppressor in various cancers, including breast cancer. Increased expression of programmed death ligand 1 (PD-L1) is frequently observed in human cancers. Despite its role in cancer cells, the effects of NDRG2 on PD-L1 ex...

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Detalles Bibliográficos
Autores principales: Lee, Aram, Lim, Soyoung, Oh, Juyeong, Lim, Jihyun, Yang, Young, Lee, Myeong-Sok, Lim, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656534/
https://www.ncbi.nlm.nih.gov/pubmed/34885221
http://dx.doi.org/10.3390/cancers13236112