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A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches

SIMPLE SUMMARY: Reliable animal models of human malignancies are paramount for preclinical studies of novel treatment approaches. Here, we successfully developed a patient-derived xenograft (PDX) model of dedifferentiated endometrial carcinoma (DEC)–an uncommon uterine malignancy that is generally u...

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Detalles Bibliográficos
Autores principales: Lin, Chiao-Yun, Wu, Ren-Chin, Huang, Chen-Yang, Lai, Chyong-Huey, Chao, An-Shine, Li, Hsin-Pai, Tsai, Chia-Lung, Kuek, Elizabeth Joo-Wen, Hsu, Cheng-Lung, Chao, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656552/
https://www.ncbi.nlm.nih.gov/pubmed/34885073
http://dx.doi.org/10.3390/cancers13235962