Cargando…

Oxidative Distress Induces Wnt/β-Catenin Pathway Modulation in Colorectal Cancer Cells: Perspectives on APC Retained Functions

SIMPLE SUMMARY: The dysregulation of Wnt pathways is involved in colorectal carcinogenesis. H(2)O(2) differentially regulates the Wnt/β-Catenin pathway in colorectal cancer (CRC), but the molecular mechanisms remain unclear. Cellular stress might also stimulate APC protein production retaining some...

Descripción completa

Detalles Bibliográficos
Autores principales: Catalano, Teresa, D’Amico, Emira, Moscatello, Carmelo, Di Marcantonio, Maria Carmela, Ferrone, Alessio, Bologna, Giuseppina, Selvaggi, Federico, Lanuti, Paola, Cotellese, Roberto, Curia, Maria Cristina, Lattanzio, Rossano, Aceto, Gitana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656656/
https://www.ncbi.nlm.nih.gov/pubmed/34885156
http://dx.doi.org/10.3390/cancers13236045