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Higher fibrotic content of endometriotic lesions is associated with diminished prostaglandin E2 signaling

PURPOSE: While the prevailing view holds that the prostaglandin E2 (PGE(2)) signaling plays a vital role in endometriosis, PGE(2) also is known to be anti‐fibrotic. We investigated the immunostaining of COX‐2, EP2, and EP4, along with fibrotic content in ovarian endometrioma (OE) and deep endometrio...

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Detalles Bibliográficos
Autores principales: Huang, Qingqing, Liu, Xishi, Guo, Sun‐Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656679/
https://www.ncbi.nlm.nih.gov/pubmed/34938147
http://dx.doi.org/10.1002/rmb2.12423