Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment

SIMPLE SUMMARY: In tissue homeostasis, aneuploid cells have been suggested to be recognized and eliminated by immune cells. However, these initiating cancer cells can evade the immune system and ultimately derivate a tumor. To better understand how aneuploidy might contribute to tumor initiation and...

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Detalles Bibliográficos
Autores principales: Alikhanyan, Kristina, Chen, Yuanyuan, Somogyi, Kalman, Kraut, Simone, Sotillo, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656692/
https://www.ncbi.nlm.nih.gov/pubmed/34885137
http://dx.doi.org/10.3390/cancers13236027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656692/
https://www.ncbi.nlm.nih.gov/pubmed/34885137
http://dx.doi.org/10.3390/cancers13236027

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