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Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment
SIMPLE SUMMARY: In tissue homeostasis, aneuploid cells have been suggested to be recognized and eliminated by immune cells. However, these initiating cancer cells can evade the immune system and ultimately derivate a tumor. To better understand how aneuploidy might contribute to tumor initiation and...
Autores principales: | Alikhanyan, Kristina, Chen, Yuanyuan, Somogyi, Kalman, Kraut, Simone, Sotillo, Rocio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656692/ https://www.ncbi.nlm.nih.gov/pubmed/34885137 http://dx.doi.org/10.3390/cancers13236027 |
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