NTRK1/TrkA Activation Overrides the G(2)/M-Checkpoint upon Irradiation

SIMPLE SUMMARY: Neuroblastoma (NB) is a solid childhood tumor and needs to be treated with multimodal therapy including radiation in advances stages. TrkA/NTRK1 expression is a hallmark of NB with excellent prognosis, but the impact of TrkA/NTRK1 on radiation response is largely unknown. Here, we re...

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Detalles Bibliográficos
Autores principales: Hassiepen, Christina, Soni, Aashish, Rudolf, Ines, Boron, Vivian, Oeck, Sebastian, Iliakis, George, Schramm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657035/
https://www.ncbi.nlm.nih.gov/pubmed/34885133
http://dx.doi.org/10.3390/cancers13236023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657035/
https://www.ncbi.nlm.nih.gov/pubmed/34885133
http://dx.doi.org/10.3390/cancers13236023

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