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Liver-Based Probabilistic Risk Assessment of Exposure to Organophosphate Esters via Dust Ingestion Using a Physiologically Based Toxicokinetic (PBTK) Model

Organophosphate esters (OPEs) are widely used and harmful to organisms and human health. Dust ingestion is an important exposure route for OPEs to humans. In this study, by integrating ToxCast high-throughput in vitro assays with in vitro to in vivo extrapolation (IVIVE) via physiologically based To...

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Detalles Bibliográficos
Autores principales: Ding, Jiaqi, Liu, Wenxin, Zhang, Hong, Zhu, Lingyan, Zhu, Lin, Feng, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657049/
https://www.ncbi.nlm.nih.gov/pubmed/34886193
http://dx.doi.org/10.3390/ijerph182312469