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Histopathological and Molecular Profiling of Clear Cell Sarcoma and Correlation with Response to Crizotinib: An Exploratory Study Related to EORTC 90101 “CREATE” Trial

SIMPLE SUMMARY: Clear cell sarcoma (CCSA) is a rare subtype of soft tissue sarcoma characterized by EWSR1 rearrangement and subsequent MET upregulation. The European Organisation for Research and Treatment of Cancer 90101 phase II trial evaluated the MET inhibitor crizotinib in CCSA but resulted in...

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Detalles Bibliográficos
Autores principales: Lee, Che-Jui, Modave, Elodie, Boeckx, Bram, Stacchiotti, Silvia, Rutkowski, Piotr, Blay, Jean-Yves, Debiec-Rychter, Maria, Sciot, Raf, Lambrechts, Diether, Wozniak, Agnieszka, Schöffski, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657105/
https://www.ncbi.nlm.nih.gov/pubmed/34885165
http://dx.doi.org/10.3390/cancers13236057