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Histopathological and Molecular Profiling of Clear Cell Sarcoma and Correlation with Response to Crizotinib: An Exploratory Study Related to EORTC 90101 “CREATE” Trial
SIMPLE SUMMARY: Clear cell sarcoma (CCSA) is a rare subtype of soft tissue sarcoma characterized by EWSR1 rearrangement and subsequent MET upregulation. The European Organisation for Research and Treatment of Cancer 90101 phase II trial evaluated the MET inhibitor crizotinib in CCSA but resulted in...
Autores principales: | Lee, Che-Jui, Modave, Elodie, Boeckx, Bram, Stacchiotti, Silvia, Rutkowski, Piotr, Blay, Jean-Yves, Debiec-Rychter, Maria, Sciot, Raf, Lambrechts, Diether, Wozniak, Agnieszka, Schöffski, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657105/ https://www.ncbi.nlm.nih.gov/pubmed/34885165 http://dx.doi.org/10.3390/cancers13236057 |
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