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CARMA3 Promotes Colorectal Cancer Cell Motility and Cancer Stemness via YAP-Mediated NF-κB Activation

SIMPLE SUMMARY: CARMA3 is overexpressed in most cancers, and its expression is positively associated with poor prognosis. In this study, we evaluated the detailed mechanisms of CARMA3-mediated CRC metastasis. We found that overexpression of CARMA3 induced the expression of YAP and NF-κB activation,...

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Detalles Bibliográficos
Autores principales: Chang, Ting-Yu, Wu, Cheng-Tien, Sheu, Meei-Ling, Yang, Rong-Sen, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657120/
https://www.ncbi.nlm.nih.gov/pubmed/34885061
http://dx.doi.org/10.3390/cancers13235946