Differential Transcriptional Reprogramming by Wild Type and Lymphoma-Associated Mutant MYC Proteins as B-Cells Convert to a Lymphoma Phenotype

SIMPLE SUMMARY: Oncogenic transformation in response to the activation of MYC requires secondary events that reduce the role of MYC as an inducer of apoptosis and cellular senescence. We made a primary B-cell model in which such secondary processes were reduced and MYC levels could be regulated at t...

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Detalles Bibliográficos
Autores principales: Mahani, Amir, Arvidsson, Gustav, Sadeghi, Laia, Grandien, Alf, Wright, Anthony P. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657136/
https://www.ncbi.nlm.nih.gov/pubmed/34885204
http://dx.doi.org/10.3390/cancers13236093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657136/
https://www.ncbi.nlm.nih.gov/pubmed/34885204
http://dx.doi.org/10.3390/cancers13236093

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