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Differential Transcriptional Reprogramming by Wild Type and Lymphoma-Associated Mutant MYC Proteins as B-Cells Convert to a Lymphoma Phenotype
SIMPLE SUMMARY: Oncogenic transformation in response to the activation of MYC requires secondary events that reduce the role of MYC as an inducer of apoptosis and cellular senescence. We made a primary B-cell model in which such secondary processes were reduced and MYC levels could be regulated at t...
Autores principales: | Mahani, Amir, Arvidsson, Gustav, Sadeghi, Laia, Grandien, Alf, Wright, Anthony P. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657136/ https://www.ncbi.nlm.nih.gov/pubmed/34885204 http://dx.doi.org/10.3390/cancers13236093 |
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