EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro Model

SIMPLE SUMMARY: Desmoplastic small round cell tumor (DSRCT) is an extremely rare soft tissue sarcoma arising in the abdomen of adolescents and young adults. This sarcoma is driven by a single genomic rearrangement, resulting in the expression of the EWSR1-WT1 fusion gene. No effective treatment exis...

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Detalles Bibliográficos
Autores principales: Bleijs, Margit, Pleijte, Corine, Engels, Sem, Ringnalda, Femke, Meyer-Wentrup, Friederike, van de Wetering, Marc, Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657306/
https://www.ncbi.nlm.nih.gov/pubmed/34885181
http://dx.doi.org/10.3390/cancers13236072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657306/
https://www.ncbi.nlm.nih.gov/pubmed/34885181
http://dx.doi.org/10.3390/cancers13236072

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