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Dysregulated TET Family Genes and Aberrant 5mC Oxidation in Breast Cancer: Causes and Consequences

SIMPLE SUMMARY: Both genetic and epigenetic mechanisms contribute to the pathogenesis of breast cancer. Since Tahiliani et al. identified TET1 as the first methyl-cytosine dioxygenase in 2009, accumulating evidence has shown that aberrant 5mC oxidation and dysregulated TET family genes are associate...

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Detalles Bibliográficos
Autores principales: Xu, Bo, Wang, Hao, Tan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657367/
https://www.ncbi.nlm.nih.gov/pubmed/34885145
http://dx.doi.org/10.3390/cancers13236039