Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis. The lack of early diagnosis and the absence of suitable biomarkers coupled with resistance to available therapeutic options has made PDAC one of the deadliest cancers. Despite advances in diagnostics and therape...

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Detalles Bibliográficos
Autores principales: Carvalho, Tiago M. A., Di Molfetta, Daria, Greco, Maria Raffaella, Koltai, Tomas, Alfarouk, Khalid O., Reshkin, Stephan J., Cardone, Rosa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657427/
https://www.ncbi.nlm.nih.gov/pubmed/34885243
http://dx.doi.org/10.3390/cancers13236135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657427/
https://www.ncbi.nlm.nih.gov/pubmed/34885243
http://dx.doi.org/10.3390/cancers13236135

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