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Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches
SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis. The lack of early diagnosis and the absence of suitable biomarkers coupled with resistance to available therapeutic options has made PDAC one of the deadliest cancers. Despite advances in diagnostics and therape...
Autores principales: | Carvalho, Tiago M. A., Di Molfetta, Daria, Greco, Maria Raffaella, Koltai, Tomas, Alfarouk, Khalid O., Reshkin, Stephan J., Cardone, Rosa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657427/ https://www.ncbi.nlm.nih.gov/pubmed/34885243 http://dx.doi.org/10.3390/cancers13236135 |
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