Adamantane-Substituted Purines and Their β-Cyclodextrin Complexes: Synthesis and Biological Activity

Cyclin-dependent kinases (CDKs) play an important role in the cell-division cycle. Synthetic inhibitors of CDKs are based on 2,6,9-trisubstituted purines and are developed as potential anticancer drugs; however, they have low solubility in water. In this study, we proved that the pharmaco-chemical p...

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Detalles Bibliográficos
Autores principales: Rouchal, Michal, Rudolfová, Jana, Kryštof, Vladimír, Vojáčková, Veronika, Čmelík, Richard, Vícha, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657435/
https://www.ncbi.nlm.nih.gov/pubmed/34884480
http://dx.doi.org/10.3390/ijms222312675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657435/
https://www.ncbi.nlm.nih.gov/pubmed/34884480
http://dx.doi.org/10.3390/ijms222312675

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