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Interleukin-35 Prevents Development of Autoimmune Diabetes Possibly by Maintaining the Phenotype of Regulatory B Cells

The anti-inflammatory role of regulatory B cells (Breg cells) has been associated with IL-35 based on studies of experimental autoimmune uveitis and encephalitis. The role of Breg cells and IL-35(+) Breg cells for type 1 diabetes (T1D) remains to be investigated. We studied PBMCs from T1D subjects a...

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Detalles Bibliográficos
Autores principales: Luo, Zhengkang, Lundin, Sara, Mejia-Cordova, Mariela, Hassani, Imane, Blixt, Martin, Hjelmqvist, Daisy, Lau, Joey, Espes, Daniel, Carlsson, Per-Ola, Sandler, Stellan, Singh, Kailash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657454/
https://www.ncbi.nlm.nih.gov/pubmed/34884797
http://dx.doi.org/10.3390/ijms222312988