Myelinosome Organelles in the Retina of R6/1 Huntington Disease (HD) Mice: Ubiquitous Distribution and Possible Role in Disease Spreading

Visual deficit is one of the complications of Huntington disease (HD), a fatal neurological disorder caused by CAG trinucleotide expansions in the Huntingtin gene, leading to the production of mutant Huntingtin (mHTT) protein. Transgenic HD R6/1 mice expressing human HTT exon1 with 115 CAG repeats r...

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Detalles Bibliográficos
Autores principales: Yefimova, Marina G., Béré, Emile, Cantereau-Becq, Anne, Meunier-Balandre, Annie-Claire, Merceron, Bruno, Burel, Agnès, Merienne, Karine, Ravel, Célia, Becq, Frédéric, Bourmeyster, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657466/
https://www.ncbi.nlm.nih.gov/pubmed/34884576
http://dx.doi.org/10.3390/ijms222312771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657466/
https://www.ncbi.nlm.nih.gov/pubmed/34884576
http://dx.doi.org/10.3390/ijms222312771

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