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Development of an Aged Full-Thickness Skin Model Using Flexible Skin-on-a-Chip Subjected to Mechanical Stimulus Reflecting the Circadian Rhythm

The skin is subject to both intrinsic aging caused by metabolic processes in the body and extrinsic aging caused by exposure to environmental factors. Intrinsic aging is an important obstacle to in vitro experimentation as its long-term progression is difficult to replicate. Here, we accelerated agi...

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Detalles Bibliográficos
Autores principales: Jeong, Subin, Kim, Jisue, Jeon, Hye Mi, Kim, Kyunghee, Sung, Gun Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8657468/
https://www.ncbi.nlm.nih.gov/pubmed/34884594
http://dx.doi.org/10.3390/ijms222312788